Journal
/
医学
/
Near Infrared Photoimmunotherapy for Mouse Models of Pleural Dissemination
JoVE 杂志
医学
需要订阅 JoVE 才能查看此.  登录或开始免费试用。
JoVE 杂志 医学
Near Infrared Photoimmunotherapy for Mouse Models of Pleural Dissemination

Near Infrared Photoimmunotherapy for Mouse Models of Pleural Dissemination

DOI:
10.3791/61593-v

•

05:39 min

•

February 09, 2021

•

, , , , ,
1Respiratory Medicine,Nagoya University Graduate School of Medicine, 2Nagoya University Institute for Advanced Research, 3B3-Unit, Advanced Analytical and Diagnostic Imaging Center (AADIC)/Medical Engineering Unit (MEU),Nagoya University Institute for Advanced Research

Chapters

  • 00:05Introduction
  • 00:31Pleural Dissemination Model Generation
  • 01:44Bioluminescence (BLI) Measurement
  • 03:02Near-Infrared Photoimmunotherapy (NIR-PIT)
  • 04:08Results: Representative NIR-PIT Thoracic Mouse Tumor Treatment
  • 05:13Conclusion

Summary

自动翻译

自动翻译

Near-infrared photoimmunotherapy (NIR-PIT) is an emerging cancer therapeutic strategy that utilizes an antibody-photoabsorber (IR700Dye) conjugate and NIR light to destroy cancer cells. Here, we present a method to evaluate the antitumor effect of NIR-PIT in a mouse model of pleural disseminated lung cancer and malignant pleural mesothelioma using bioluminescence imaging.

Tags

Keywords: Near Infrared PhotoimmunotherapyPleural DisseminationMouse ModelBioluminescence ImagingD-luciferin690-nanometer LaserLight Dose

Article

Embed

添加到播放列表

Usage Statistics

Related Videos

check_url/cn/61593?article_type=v

In vivo Near Infrared Fluorescence (NIRF) Intravascular Molecular Imaging of Inflammatory Plaque, a Multimodal Approach to Imaging of Atherosclerosis
check_url/cn/61593?article_type=v

Near Infrared Optical Projection Tomography for Assessments of β-cell Mass Distribution in Diabetes Research
check_url/cn/61593?article_type=v

Mouse Models for Graft Arteriosclerosis
check_url/cn/61593?article_type=v

Tissue-simulating Phantoms for Assessing Potential Near-infrared Fluorescence Imaging Applications in Breast Cancer Surgery
check_url/cn/61593?article_type=v

Mouse Kidney Transplantation: Models of Allograft Rejection
check_url/cn/61593?article_type=v

High-frequency Ultrasound Imaging of Mouse Cervical Lymph Nodes
check_url/cn/61593?article_type=v

Combined Near-infrared Fluorescent Imaging and Micro-computed Tomography for Directly Visualizing Cerebral Thromboemboli
check_url/cn/61593?article_type=v

Bioluminescence and Near-infrared Imaging of Optic Neuritis and Brain Inflammation in the EAE Model of Multiple Sclerosis in Mice
check_url/cn/61593?article_type=v

Skeletal Muscle Neurovascular Coupling, Oxidative Capacity, and Microvascular Function with ‘One Stop Shop’ Near-infrared Spectroscopy
check_url/cn/61593?article_type=v

A New Best Practice for Validating Tail Vein Injections in Rat with Near-infrared-Labeled Agents

Read Article