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Sporing Superparamagnetic Iron oksid-merket Mesenchymal stamceller bruker MRI etter intranasal levering i en traumatisk hjerneskade murine modell
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November 21, 2019
DOI:
1Ph.D. Program for Neural Regenerative Medicine, College of Medical Science and Technology,Taipei Medical University and National Health Research Institutes, 2Center for Neurotrauma and Neuroregeneration,Taipei Medical University, 3TMU Neuroscience Research Center,Taipei Medical University, 4Department of Neurosurgery,Taipei Medical University Hospital, 5Department of Surgery, School of Medicine, College of Medicine,Taipei Medical University
Summary
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Presentert her er en protokoll for ikke-invasiv mesenchymal Stem Cell (MSC) levering og sporing i en mus modell av traumatisk hjerneskade. Superparamagnetic jernoksid nanopartikler anvendes som en MRI-sonde (magnetisk resonans imaging) for MSC-merking og ikke-invasiv in vivo-sporing etter intranasal levering med sann tids MRI.
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Cite this Article
Shahror, R. A., Wu, C., Chiang, Y., Chen, K. Tracking Superparamagnetic Iron Oxide-labeled Mesenchymal Stem Cells using MRI after Intranasal Delivery in a Traumatic Brain Injury Murine Model. J. Vis. Exp. (153), e60450, doi:10.3791/60450 (2019).
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