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跟踪超副磁性氧化铁标记的美感血干细胞使用MRI后,创伤性脑损伤Murine模型内伤分娩
JoVE 杂志
医学
This content is Free Access.
JoVE 杂志 医学
Tracking Superparamagnetic Iron Oxide-labeled Mesenchymal Stem Cells using MRI after Intranasal Delivery in a Traumatic Brain Injury Murine Model
DOI:

10:03 min

November 21, 2019

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Chapters

  • 00:05Title
  • 01:06Superparamagnetic Iron Oxide (SPIO) nanoParticles labeling of Mesenchymal Stem Cells (MSC)
  • 01:44Controlled Cortical Impact (CCI) Injury
  • 04:04Intranasal MSC Delivery
  • 05:57In Vivo Magnetic Resonance Imaging (MRI)
  • 06:54MSC Tracking and Quantification
  • 08:03Results: Representative SPIO-Labeled MSC Detection and Tracking
  • 09:08Conclusion

Summary

自动翻译

这里介绍的是一个非侵入性的中伤性干细胞(MSC)传递和跟踪的小鼠模型创伤性脑损伤的协议。超对磁氧化铁纳米颗粒用作磁共振成像(MRI)探头,用于MSC标签和非侵入性体内跟踪,使用实时MRI进行鼻内传递。

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