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Abbiategrasso Brain Bank Protocol for Collecting, Processing and Characterizing Aging Brains
JoVE 杂志
神经科学
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JoVE 杂志 神经科学
Abbiategrasso Brain Bank Protocol for Collecting, Processing and Characterizing Aging Brains

Abbiategrasso Brain Bank Protocol for Collecting, Processing and Characterizing Aging Brains

16,748 Views

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12:28 min

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June 03, 2020

DOI:

10.3791/60296-v

DOI:
10.3791/60296-v

•

12:28 min
June 03, 2020

•

15 Views
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1Department of Neurology and Neuropathology,Golgi-Cenci Foundation, 2Laboratory of Neurobiology and Neurogenetic,Golgi-Cenci Foundation, 3Department of Neuropsychology and Social Sciences,Golgi-Cenci Foundation, 4Department of Rehabilitation,ASP Golgi-Redaelli Geriatric Hospital, 5Genomic and Post-Genomic Center,IRCCS Mondino Foundation, 6Department of Brain and Behavioral Sciences,University of Pavia, 7Department of Pathology,ASP Golgi-Redaelli Geriatric Hospital, 8Department of Neurological Science, IRCCS Mondino Foundation,University of Pavia

Summary

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This protocol describes a method to track individual brain-aging trajectories through a brain donation program and proper characterization of brains. Brain donors are involved in a long-term longitudinal study including serial multi-dimensional assessments. The protocol contains a detailed description of brain processing and an accurate diagnostic methodology.

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Poloni, T. E., Medici, V., Carlos, A. F., Davin, A., Ceretti, A., Mangieri, M., Cassini, P., Vaccaro, R., Zaccaria, D., Abbondanza, S., Bordoni, M., Fantini, V., Fogato, E., Cereda, C., Ceroni, M., Guaita, A. Abbiategrasso Brain Bank Protocol for Collecting, Processing and Characterizing Aging Brains. J. Vis. Exp. (160), e60296, doi:10.3791/60296 (2020).

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