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Investigating Long-term Synaptic Plasticity in Interlamellar Hippocampus CA1 by Electrophysiological Field Recording
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神经科学
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JoVE 杂志 神经科学
Investigating Long-term Synaptic Plasticity in Interlamellar Hippocampus CA1 by Electrophysiological Field Recording

Investigating Long-term Synaptic Plasticity in Interlamellar Hippocampus CA1 by Electrophysiological Field Recording

DOI:
10.3791/59879-v

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14:27 min

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August 11, 2019

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, , , ,
1Department of Biomedical Sciences,City University of Hong Kong, 2Department of Nano-Bioengineering,Incheon National University, 3Division of Life Sciences, College of Life Sciences and Bioengineering,Incheon National University

Chapters

  • 00:00Title
  • 01:00Animal Preparation: Draining of Cerebrospinal Fluid
  • 02:35Animal Preparation: Craniotomy
  • 04:22Data Acquisition: In Vivo
  • 06:06In Vitro Setup
  • 07:10Brain Slicing
  • 11:00Data Acquisition: In Vitro
  • 12:48Results
  • 13:43Conclusion

Summary

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自动翻译

We used recording and stimulation electrodes in longitudinal hippocampal brain slices and longitudinally positioned recording and stimulation electrodes in the dorsal hippocampus in vivo to evoke extracellular postsynaptic potentials and demonstrate long-term synaptic plasticity along the longitudinal interlamellar CA1.

Tags

Long-term Synaptic PlasticityLong-term PotentiationLong-term DepressionHippocampus CA1Electrophysiological Field RecordingLongitudinal OrientationAssociational ConnectionsUrethane AnesthesiaStereotaxic SurgeryCerebrospinal Fluid DrainageStimulation And Recording ElectrodesDorsal Hippocampus CA1

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