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评估介入疗法对人体粪便微生物群影响的体内批处理培养模型

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An In Vitro Batch-culture Model to Estimate the Effects of Interventional Regimens on Human Fecal Microbiota

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评估介入疗法对人体粪便微生物群影响的体内批处理培养模型

9,201 Views

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07:15 min

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July 31, 2019

DOI:

10.3791/59524-v

DOI:

10.3791/59524-v

•

07:15 min

July 31, 2019

•

19 Views

Shokouh Ahmadi*^1,2,3, Shaohua Wang*^1,2, Ravinder Nagpal*^1,2, Rabina Mainali^1,2, Sabihe Soleimanian-Zad^3,4, Dalane Kitzman⁵, Hariom Yadav^1,2

¹Department of Internal Medicine- Molecular Medicine,Wake Forest School of Medicine, ²Department of Microbiology and Immunology,Wake Forest School of Medicine, ³Department of Food Science and Technology,Isfahan University of Technology, ⁴Research Institute for Biotechnology and Bioengineering, College of Agriculture,Isfahan University of Technology, ⁵Department of Geriatrics and Gerontology,Wake Forest School of Medicine

Summary

该协议描述了人类粪便微生物群的体外批量培养发酵系统,使用硫素(一种众所周知的益生菌和研究最广泛的微生物群调制器之一)来证明该系统在估计特定效果时的使用粪便微生物群成分和代谢活动的干预措施。

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