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Highly Efficient Gene Disruption of Murine and Human Hematopoietic Progenitor Cells by CRISPR/Cas9

JoVE 杂志
遗传学

This content is Free Access.

JoVE 杂志遗传学

Highly Efficient Gene Disruption of Murine and Human Hematopoietic Progenitor Cells by CRISPR/Cas9

Highly Efficient Gene Disruption of Murine and Human Hematopoietic Progenitor Cells by CRISPR/Cas9

12,947 Views

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08:27 min

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April 10, 2018

DOI:

10.3791/57278-v

DOI:

10.3791/57278-v

•

08:27 min

April 10, 2018

•

1 Views

Lorenzo Brunetti*^1,2,3, Michael C. Gundry*^1,2,4, Ayumi Kitano, Daisuke Nakada^2,4, Margaret A. Goodell^2,4,5

¹Stem Cells & Regenerative Medicine Center,Baylor College of Medicine, ²Center for Cell and Gene Therapy,Baylor College of Medicine, ³Centro di Ricerca Emato-Oncologica (CREO),University of Perugia, ⁴Department of Molecular & Human Genetics,Baylor College of Medicine, ⁵Texas Children’s Hospital & Houston Methodist Hospital

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