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Orthotopic Ovarian Transplantation Procedures to Investigate the Life- and Health-span Influence of Ovarian Senescence in Female Mice
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发育生物学
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JoVE 杂志 发育生物学
Orthotopic Ovarian Transplantation Procedures to Investigate the Life- and Health-span Influence of Ovarian Senescence in Female Mice

Orthotopic Ovarian Transplantation Procedures to Investigate the Life- and Health-span Influence of Ovarian Senescence in Female Mice

DOI:
10.3791/56638-v

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06:49 min

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February 12, 2018

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, ,
1Department of Animal, Dairy and Veterinary Sciences, Center for Integrated BioSystems, School of Veterinary Medicine,Utah State University

Chapters

  • 00:04Title
  • 00:59Intact Ovary Harvest
  • 03:32Intact Ovary Transplantation
  • 04:56Results: Representative Effects of Ovarian Transplant and Small Follicle Depletion in CBA/J Mice
  • 06:21Conclusion

Summary

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自动翻译

Described here are orthotopic ovarian transplantation protocols for modifying ovarian influence on the physiology of the recipient mouse. This surgical procedure is used to expose female mice to various types of ovarian influence and may include heterochronic transplantations and transplantation of ovaries that have undergone various ex vivo treatments.

Tags

Orthotopic Ovarian TransplantationOvarian SenescenceFemale MiceReproductive AgingOvarian SignalingMenopauseOvarian InsufficiencySurgical ProcedureOvary Transplant

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