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1Molecular Neuropharmacology and Genetics Laboratory, Lundbeck Foundation Center for Biomembranes in Nanomedicine, Department of Neuroscience and Pharmacology, Faculty of Health and Medical Sciences,University of Copenhagen, 2Laboratory of Neuropsychiatry, Psychiatric Center Copenhagen and Department of Neuroscience and Pharmacology,University of Copenhagen
Chapters
- 00:05Title
- 01:00Synaptosomal Preparation
- 03:22Uptake Experiment
- 07:00High-performance Liquid Chromatography Analysis
- 09:19Results: Representative Results from a Synaptosomal DA Uptake Experiment of Four C57BI/6 Wild Type Mice from Drd1a-cre Mouse Strain
- 10:40Conclusion
Synaptosomal dopamin opptak og høy ytelse flytende kromatografi representerer eksperimentelle verktøy undersøke dopamin homeostase i mus ved å vurdere funksjon av dopamin transporter og nivåer av dopamin i striatal vev, henholdsvis. Her presenterer vi for å måle dopamin vev innhold og vurdere funksjonaliteten til den dopamin transporter.
