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Assessing Spatial Memory Impairment in a Mouse Model of Traumatic Brain Injury Using a Radial Water Tread Maze
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Assessing Spatial Memory Impairment in a Mouse Model of Traumatic Brain Injury Using a Radial Water Tread Maze

Assessing Spatial Memory Impairment in a Mouse Model of Traumatic Brain Injury Using a Radial Water Tread Maze

6,943 Views

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06:09 min

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July 17, 2017

DOI:

10.3791/55986-v

DOI:
10.3791/55986-v

•

06:09 min
July 17, 2017

•

3 Views
, , , , ,
1Department of Radiology,University of Washington, 2Department of Radiology,University of Utah, 3Geriatric Research Education and Clinical Center (GRECC),VA Puget Sound

Summary

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Here we present a protocol for a mouse-specific test of cognition that does not require swimming. This test can be used to successfully distinguish controlled cortical impact-induced traumatic brain injury mice from sham controls.

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Cite this Article

Cline, M. M., Ostlie, M. A., Cross, C. G., Garwin, G. G., Minoshima, S., Cross, D. J. Assessing Spatial Memory Impairment in a Mouse Model of Traumatic Brain Injury Using a Radial Water Tread Maze. J. Vis. Exp. (125), e55986, doi:10.3791/55986 (2017).

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