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Automotive Radiochemical Synthesis of [<sup> 18</sup> F] 3F4AP: Um novo marcador de PET para imagens de doenças desmielinizantes
JoVE 杂志
医学
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JoVE 杂志 医学
Automated Radiochemical Synthesis of [18F]3F4AP: A Novel PET Tracer for Imaging Demyelinating Diseases

Automotive Radiochemical Synthesis of [<sup> 18</sup> F] 3F4AP: Um novo marcador de PET para imagens de doenças desmielinizantes

9,657 Views

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11:03 min

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May 29, 2017

DOI:

10.3791/55537-v

DOI:
10.3791/55537-v

•

11:03 min
May 29, 2017

•

2 Views
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1Department of Neurology,The University of Chicago, 2Department of Radiology,The University of Chicago

Summary

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Demonstramos a síntese radioquímica semi-automatizada de [18F] 3F4AP e procedimentos de controle de qualidade.

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[18F]3F4APPET TracerDemyelinating DiseasesAutomated Radiochemical SynthesisFluorine-18HydrogenationSolid Phase ExtractionHPLC

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Brugarolas, P., Bhuiyan, M., Kucharski, A., Freifelder, R. Automated Radiochemical Synthesis of [18F]3F4AP: A Novel PET Tracer for Imaging Demyelinating Diseases. J. Vis. Exp. (123), e55537, doi:10.3791/55537 (2017).

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