需要订阅 JoVE 才能查看此. 登录或开始免费试用。
인간 인플루엔자 바이러스 감염의 Zebrafish의 모델을 사용하여 항 바이러스 약품을 화면 및 호스트 면역 세포 반응의 특성을
9,678 Views
•
09:07 min
•
January 20, 2017
DOI:
1Department of Molecular and Biomedical Sciences,University of Maine, 2Graduate School of Biomedical Sciences and Engineering,University of Maine, 3School of Biology and Ecology,University of Maine, 4Division of Intramural Research, Immunity, Inflammation and Disease Laboratory,National Institute of Environmental Health Sciences, NIH, 5Department of Chemical and Biological Engineering,University of Maine
Summary
Automatically generated
Systemic and localized zebrafish infection models for human influenza A virus are demonstrated. Using a systemic infection model, zebrafish can be used to screen antiviral drugs. Using a localized infection model, zebrafish can be used to characterize host immune cell responses.
Read Article
Cite this Article
Sullivan, C., Jurcyzszak, D., Goody, M. F., Gabor, K. A., Longfellow, J. R., Millard, P. J., Kim, C. H. Using Zebrafish Models of Human Influenza A Virus Infections to Screen Antiviral Drugs and Characterize Host Immune Cell Responses. J. Vis. Exp. (119), e55235, doi:10.3791/55235 (2017).
Copy