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Bildgestützte, laserbasierte Herstellung von Mikrofluidik-Networks-Vascular abgeleitet
JoVE 杂志
生物工程
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JoVE 杂志 生物工程
Image-guided, Laser-based Fabrication of Vascular-derived Microfluidic Networks
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Bildgestützte, laserbasierte Herstellung von Mikrofluidik-Networks-Vascular abgeleitet

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10:53 min

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January 03, 2017

DOI:

10.3791/55101-v

DOI:
10.3791/55101-v

•

10:53 min
January 03, 2017

•

1 Views
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1Department of Biomedical Engineering,University of Delaware, 2Department of Electrical and Computer Engineering,University of Houston, 3Delaware Biotechnology Institute

Summary

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This protocol outlines the implementation of image-guided, laser-based hydrogel degradation to fabricate vascular-derived, biomimetic microfluidic networks embedded in poly(ethylene glycol) diacrylate (PEGDA) hydrogels. These biomimetic microfluidic systems may be useful for tissue engineering applications, generation of in vitro disease models, and fabrication of advanced "on-a-chip" devices.

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Image-guidedLaser-basedFabricationVascular-derivedMicrofluidic NetworksConfocal MicroscopeFemtosecond Pulse LaserPolyethylene Glycol DiacrylateHydrogelsLaser-based DegradationBiomimetic Microfluidic NetworksDisease ModelsOn-chip DevicesPhotopolymerizationPEGDAEosin YNVPPDMS Mold

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Heintz, K. A., Mayerich, D., Slater, J. H. Image-guided, Laser-based Fabrication of Vascular-derived Microfluidic Networks. J. Vis. Exp. (119), e55101, doi:10.3791/55101 (2017).

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