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聴覚弁別学習した後、マウス脳領域の高分解能定量的シナプスプロテオームプロファイリング
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December 15, 2016
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The identification of molecules and pathways controlling synaptic plasticity and memory is still a major challenge in neuroscience. Here, a workflow is described addressing the relative quantification of synaptic proteins supposedly involved in the molecular reorganization of synapses during learning and memory consolidation in an auditory learning paradigm.
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Kolodziej, A., Smalla, K., Richter, S., Engler, A., Pielot, R., Dieterich, D. C., Tischmeyer, W., Naumann, M., Kähne, T. High Resolution Quantitative Synaptic Proteome Profiling of Mouse Brain Regions After Auditory Discrimination Learning. J. Vis. Exp. (118), e54992, doi:10.3791/54992 (2016).
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