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Aplicaciones de la<em> En Vivo</em> Pruebas funcionales de la rata tibial anterior para la evaluación de la ingeniería tisular de reparación del músculo esquelético
JoVE 杂志
生物工程
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JoVE 杂志 生物工程
Applications of In Vivo Functional Testing of the Rat Tibialis Anterior for Evaluating Tissue Engineered Skeletal Muscle Repair
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Aplicaciones de la<em> En Vivo</em> Pruebas funcionales de la rata tibial anterior para la evaluación de la ingeniería tisular de reparación del músculo esquelético

13,316 Views

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07:13 min

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October 07, 2016

DOI:

10.3791/54487-v

DOI:
10.3791/54487-v

•

07:13 min
October 07, 2016

•

7 Views
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1Department of Pathology,University of Virginia, 2Department of Biomedical Engineering,University of Virginia, 3Department of Orthopaedic Surgery,University of Virginia

Summary

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We describe an in vivo protocol to measure dorsiflexion of the foot following stimulation of the peroneal nerve and contraction of the anterior crural compartment of the rat hindlimb. Such measurements are an indispensable translational tool for evaluating skeletal muscle pathology and tissue engineering approaches to muscle repair and regeneration.

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Cite this Article

Mintz, E. L., Passipieri, J. A., Lovell, D. Y., Christ, G. J. Applications of In Vivo Functional Testing of the Rat Tibialis Anterior for Evaluating Tissue Engineered Skeletal Muscle Repair. J. Vis. Exp. (116), e54487, doi:10.3791/54487 (2016).

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