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그라데이션 원심 분리에 의해 인플루엔자 A 바이러스 캡시드의 생체 외 분해에
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免疫与感染
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JoVE 杂志 免疫与感染
In Vitro Disassembly of Influenza A Virus Capsids by Gradient Centrifugation

그라데이션 원심 분리에 의해 인플루엔자 A 바이러스 캡시드의 생체 외 분해에

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07:24 min

March 27, 2016

DOI:

07:24 min
March 27, 2016

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Summary

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Disassembly of influenza A virus cores during virus entry into host cells is a multistep process. We describe an in vitro method to analyze the early stages of viral uncoating. In this approach, velocity gradient centrifugation is used to biochemically dissect the steps that initiate uncoating under defined conditions.

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