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Chapters
- 00:05Title
- 01:28Mounting the NMJ Samples
- 02:48Measuring Nuclei Density within a Muscle Fiber
- 05:06Shape Analysis of the Muscle Fiber Nuclei
- 06:523D Volume Renderings of Muscle Fiber Nuclei
- 08:22Results: Analysis of ALS-like Symptoms
- 09:38Conclusion
Morphology, size and location of intracellular organelles are evolutionarily conserved and appear to directly affect their function. Understanding the molecular mechanisms underlying these processes has become an important goal of modern biology. Here we show how these studies can be facilitated by the application of quantitative techniques.
