Journal
/
生物工程
/
在心肌结构，功能的体内定量评估，灌注与活力使用心脏微型计算机断层扫描
JoVE 杂志
生物工程
This content is Free Access.
JoVE 杂志 生物工程
In Vivo Quantitative Assessment of Myocardial Structure, Function, Perfusion and Viability Using Cardiac Micro-computed Tomography
Please note that all translations are automatically generated. Click here for the English version.

在心肌结构，功能的体内定量评估，灌注与活力使用心脏微型计算机断层扫描

18,944 Views

•

08:13 min

•

February 16, 2016

DOI:

10.3791/53603-v

DOI:
10.3791/53603-v

•

08:13 min
February 16, 2016

•

11 Views
, , , ,
1Department of Genetics,Erasmus MC, Rotterdam, 2Department of Experimental Cardiology,Erasmus MC, Rotterdam, 3PerkinElmer, Inc., 4Department of Vascular Surgery,Erasmus MC, Rotterdam, 5Department of Radiation Oncology,Erasmus MC, Rotterdam

Summary

Automatically generated

This method outlines the use of Quantum Micro-Computed Tomography (MicroCT) to assess cardiac morphology, function, perfusion, metabolism and viability with iodinated contrast agent in mice with experimentally-induced myocardial ischemia. The technique can be applied for non-destructive high-throughput longitudinal in vivo imaging of various animal models of human heart disease.

Explore More Videos

Cardiac Micro-computed TomographyMyocardial StructureMyocardial FunctionMyocardial PerfusionMyocardial ViabilityCardiac IschemiaCardiac PathophysiologyCardiac Disease DevelopmentCardiac ParametersNon-invasive EvaluationPreclinical ToolMouse ModelLeft Coronary Artery LigationInfarct InductionMicroCT Imaging

Read Article

Cite this Article

van Deel, E., Ridwan, Y., van Vliet, J. N., Belenkov, S., Essers, J. In Vivo Quantitative Assessment of Myocardial Structure, Function, Perfusion and Viability Using Cardiac Micro-computed Tomography. J. Vis. Exp. (108), e53603, doi:10.3791/53603 (2016).

Download .ris file

Copy

Share Video

.

Copy