Monocytes are key regulators of innate immunity and play a critical role in the renewal of the peripheral mononuclear phagocytic system and in case of inflammation. This manuscript describes the procedure of real time imaging of the mouse calvaria bone marrow to study the monocyte mobilisation mechanism.
Hamon, P., Rodero, M. P., Combadière, C., Boissonnas, A. Tracking Mouse Bone Marrow Monocytes In Vivo. J. Vis. Exp. (96), e52476, doi:10.3791/52476 (2015).