The most studied aspect of the biocompatibility of dental composites is their cytotoxicity 3D CLSM time lapse imaging combined with fluorescent signal quantification allows sensitive evaluation of the cell fate over time. Utilizing this method could be an efficient tool to assess the cytocompatibility of dental composites.
Attik, G. N., Gritsch, K., Colon, P., Grosgogeat, B. Confocal Time Lapse Imaging as an Efficient Method for the Cytocompatibility Evaluation of Dental Composites. J. Vis. Exp. (93), e51949, doi:10.3791/51949 (2014).