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Microstereolithography和静电结合，以产生膜配备有利基的角膜再生

JoVE 杂志
生物工程

This content is Free Access.

JoVE 杂志生物工程

Combination of Microstereolithography and Electrospinning to Produce Membranes Equipped with Niches for Corneal Regeneration

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Microstereolithography和静电结合，以产生膜配备有利基的角膜再生

DOI:

10.3791/51826-v

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11:42 min

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September 12, 2014

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Ílida Ortega, Farshid Sefat, Pallavi Deshpande, Thomas Paterson, Charanya Ramachandran, Anthony J. Ryan, Sheila MacNeil, Frederik Claeyssens

¹Department of Materials Science and Engineering,University of Sheffield, ²Department of Chemistry,University of Sheffield, ³L. V. Prasad Eye Institute

Chapters

00:05Title
02:15Fabrication of PEGDA Templates by Microstereolithography
03:58Fabrication of Biodegradable PLGA Membranes Using Electrospinning
05:48Long-term Storage of PLGA Microfabricated Membranes
06:34Isolation of Limbal Explants
07:53Inclusion of Ring Scaffolds in Rabbit Cornea 3D Models
08:46Results: Synthetic Microstructured Membranes Support Corneal Regeneration
10:48Conclusion

Summary

自动翻译

我们报告的静电膜，用来研究细胞行为中micropockets的制造技术。具体地，我们描述了用于生产的PLGA（聚（丙交酯 - 共 - 乙））配备有微特征角膜生物材料的设备microstereolithography和静电纺丝的组合。

Tags

Keywords: Corneal Regeneration Microstereolithography Electrospinning Corneal Membranes Limbal Stem Cells Palisades Of Vogt Corneal Disease Corneal Grafts Stem Cell Carriers Corneal Biomaterial Devices Platform Technology

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