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从人多能干细胞定向多巴胺能神经元分化
JoVE 杂志
神经科学
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JoVE 杂志 神经科学
Directed Dopaminergic Neuron Differentiation from Human Pluripotent Stem Cells
DOI:

06:40 min

September 15, 2014

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Chapters

  • 00:05Title
  • 01:11Preparation of Cells for Differentiation
  • 03:00Cell Differentiation
  • 04:39Results: Representative Dopaminergic Neuron Images
  • 06:13Conclusion

Summary

自动翻译

We, based on knowledge from developmental biology and published research, developed an optimized protocol to efficiently generate A9 midbrain dopaminergic neurons from both human embryonic stem cells and human induced pluripotent stem cells, which would be useful for disease modeling and cell replacement therapy for Parkinson’s disease.

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