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Marble Burying and Nestlet Shredding as Tests of Repetitive, Compulsive-like Behaviors in Mice
Chapters
- 00:05Title
- 01:22Animal Handling
- 01:48Marble Burying Test
- 03:26Nestlet Shredding Test
- 04:47Results: Compulsive-like Behaviors in Mice
- 06:10Conclusion
Disease, head injury, genetic modifications, and treatment of mice with drugs can have profound effects on behavior. Utilizing well-characterized and validated approaches such as marble burying and nestlet shredding, compulsive-like behaviors can be documented accurately in mice as models of human obsessive-compulsive disorder and autism spectrum disorder.
