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Journal / Medicine / Experimental Human Pneumococcal Carriage
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JoVE Journal Medicine
Experimental Human Pneumococcal Carriage
 

Experimental Human Pneumococcal Carriage

Article DOI: 10.3791/50115-v • 07:47 min • February 15th, 2013
February 15th, 2013 •
1, 1,2,3, 1,2,4, 1, 5, 6, 1, 1
1Respiratory Infection Group, Liverpool School of Tropical Medicine, 2Royal Liverpool and Broadgreen, University Hospital Trust, 3Comprehensive Local Research Network, 4NIHR Biomedical Research Centre in Microbial Diseases, Royal Liverpool and Broadgreen University Hospitals NHS Trust, 5Institute of Lung Health, Respiratory Biomedical Unit, University Hospitals of Leicester NHS Trust & University of Leicester, 6Department of Clinical Infection Microbiology & Immunology, Institute of Infection & Global Health, University of Liverpool

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总结概括
Automatic Translation

Experimental human pneumococcal carriage offers a natural model of carriage and a potential model for use in vaccine development. This technique is valuable yet complex and involves clinical risk by introducing a pathogen into a human. We have developed a detailed protocol.

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Experimental Human Pneumococcal Carriage EHPC Streptococcus Pneumoniae Nasopharyngeal Carriage Invasive Disease Immunological Correlates Of Protection Immunizing Effect Host Pressure Pathogen Nasopharyngeal Niche Carriage Detection Epidemiologic Studies Vaccine Studies Novel Pneumococcal Vaccines Prevention Of Carriage Vaccine Induced Immunity Conjugate Vaccines Non-bacteraemic Pneumonia Serotype Replacement
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