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Electrospinning Fundamentals: Optimizing Solution and Apparatus Parameters
JoVE 杂志
生物工程
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JoVE 杂志 生物工程
Electrospinning Fundamentals: Optimizing Solution and Apparatus Parameters

Electrospinning Fundamentals: Optimizing Solution and Apparatus Parameters

DOI:
10.3791/2494-v

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07:57 min

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January 21, 2011

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, , ,
1Department of Biomedical Engineering,University of Michigan, 2State Key Laboratory of Bioelectronics,Southeast University, 3Department of Neurology,University of Michigan, 4Geriatrics Research, Education and Clinical Center,Veterans Affairs Ann Arbor Healthcare Center

Chapters

  • 00:00Title
  • 00:58Introduction
  • 01:17Choose a Polymer and a Collector
  • 02:23The Critical Entanglement Concentration
  • 03:42Troubleshooting: The Stream
  • 05:39Troubleshooting: Fiber Morphology
  • 06:59Electrospun Nanofiber Scaffolds for Cells
  • 07:24Conclusion

Summary

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Electrospinning techniques can create a variety of nanofibrous scaffolds for tissue engineering or other applications. We describe here a procedure to optimize the parameters of the electrospinning solution and apparatus to obtain fibers with the desired morphology and alignment. Common problems and troubleshooting techniques are also presented.

Tags

ElectrospinningNanofiber ScaffoldsPolymer JetGrounded CollectorRapidly Rotating CollectorStationary CollectorCritical Entanglement ConcentrationStable JetStreaming SegmentWhipping SegmentAlignment Of NanofibersMorphology Of NanofibersSolution CompositionElectrospinning Apparatus Configuration

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