JOVE JOURNAL

癌症研究

Showing 169 - 180 in 611 videos.

Intra-Peritoneal Transplantation for Generating Acute Myeloid Leukemia in Mice

Fenghua Qian¹, Brooke E. Arner¹, Shaneice K. Nettleford¹, Robert F. Paulson¹, K. Sandeep Prabhu¹

¹Department of Veterinary and Biomedical Sciences, Center for Molecular Immunology and Infectious Disease and Center for Molecular Toxicology and Carcinogenesis, Penn State Cancer Institute,The Pennsylvania State University

Journal (Cancer Research)

Modeling Oral-Esophageal Squamous Cell Carcinoma in 3D Organoids

Samuel Flashner*¹, Cecilia Martin*^1,2, Norihiro Matsuura¹, Masataka Shimonosono¹, Yasuto Tomita¹, Masaki Morimoto¹, Ogoegbunam Okolo¹, Victoria X. Yu^1,3, Anuraag S. Parikh^1,3, Andres J. P. Klein-Szanto⁴, Kelley Yan^1,2, Joel T. Gabre^1,5, Chao Lu^1,6, Fatemeh Momen-Heravi^1,7, Anil K. Rustgi^1,5, Hiroshi Nakagawa^1,2,5

¹Herbert Irving Comprehensive Cancer Center,Columbia University, ²Organoid and Cell Culture Core, Columbia University Digestive and Liver Diseases Research Center,Columbia University, ³Department of Otolaryngology, Head and Neck Surgery,Columbia University, ⁴Histopathology Facility,Fox Chase Cancer Center, ⁵Division of Digestive and Liver Diseases, Department of Medicine,Columbia University, ⁶Department of Genetics and Development,Columbia University, ⁷Section of Oral, Diagnostic and Rehabilitation Sciences, College of Dental Medicine,Columbia University

Journal (Cancer Research)

Multiparametric Tumor Organoid Drug Screening Using Widefield Live-Cell Imaging for Bulk and Single-Organoid Analysis

Maxim Le Compte¹, Edgar Cardenas De La Hoz², Sofía Peeters¹, Evelien Smits¹, Filip Lardon¹, Geert Roeyen^1,3, Steve Vanlanduit², Hans Prenen^1,4, Marc Peeters^1,4, Abraham Lin^1,5, Christophe Deben¹

¹Center for Oncological Research (CORE), Integrated Personalized & Precision Oncology Network (IPPON),University of Antwerp, ²Industrial Vision Lab,University of Antwerp, ³Department of Hepatobiliary Transplantation and Endocrine Surgery,University Hospital Antwerp (UZA), ⁴Department of Oncology,University Hospital Antwerp (UZA), ⁵Plasma Lab for Applications in Sustainability and Medicine ANTwerp (PLASMANT),University of Antwerp

Journal (Cancer Research)

Testing Cancer Immunotherapeutics in a Humanized Mouse Model Bearing Human Tumors

Jordi M. Lanis*¹, Matthew S. Lewis*¹, Hannah Strassburger¹, Kristina Larsen¹, Stacey M. Bagby², Adrian T. A. Dominguez², Juan A. Marín-Jiménez³, Roberta Pelanda¹, Todd M. Pitts², Julie Lang¹

¹Department of Immunology and Microbiology, School of Medicine,University of Colorado Denver Anschutz Medical Campus, ²Division of Oncology, School of Medicine,University of Colorado Denver Anschutz Medical Campus, ³Department of Medical Oncology,Catalan Institute of Oncology (ICO-L'Hospitalet)

Journal (Cancer Research)

Establishing 3-Dimensional Spheroids from Patient-Derived Tumor Samples and Evaluating their Sensitivity to Drugs

Neta Moskovits^1,2, Ella Itzhaki^1,2, Nataly Tarasenko^1,2, Eva Chausky^1,2, Avital Bareket-Samish³, Aleksandr Kaufman^1,2, Raisa Meerson^1,2, Salomon M. Stemmer^1,2,4

¹Felsenstein Medical Research Center, ²Davidoff Center, Rabin Medical Center, ³BioInsight Ltd., ⁴Sackler Faculty of Medicine,Tel Aviv University

Journal (Cancer Research)

Culture and Imaging of Ex Vivo Organotypic Pseudomyxoma Peritonei Tumor Slices from Resected Human Tumor Specimens

Jonathan Weitz¹, Kevin Christian Montecillo Gulay¹, Tatiana Hurtado de Mendoza¹, Herve Tiriac¹, Joel Baumgartner¹, Kaitlyn Kelly¹, Jula Veerapong¹, Andrew M. Lowy¹

¹Department of Surgery,University of California

Journal (Cancer Research)

X-Ray Visualization of Intraductal Ethanol-Based Ablative Treatment for Prevention of Breast Cancer in Rat Models

Elizabeth Kenyon^1,2, Erin Zaluzec^1,3, Katherine Powell^1,2, Maximilian Volk^1,4, Shatadru Chakravarty^2,5, Jeremy Hix^2,6, Matti Kiupel⁷, Erik M. Shapiro², Lorenzo F. Sempere^1,2

¹Precision Health Program,Michigan State University, ²Department of Radiology,Michigan State University, ³Department of Pharmacology & Toxicology,Michigan State University, ⁴College of Osteopathic Medicine,Michigan State University, ⁵TechInsights Inc., ⁶IQ Advanced Molecular Imaging Facility,Michigan State University, ⁷Veterinary Diagnostic Laboratory, College of Veterinary Medicine,Michigan State University

Journal (Cancer Research)

Implantation and Evaluation of Melanoma in the Murine Choroid via Optical Coherence Tomography

Dimitri Gaber¹, Michal Aharoni-Simon¹, Ortal Zaks¹, Keren Ben-Yaakov¹, Ziv Rotfogel^1,2, Hana Leiba^1,2, Avital Eisenberg-Lerner*¹, Arie L. Marcovich*^1,2

¹Ophthalmology Research Laboratory,Kaplan Medical Center, ²Department of Ophthalmology, Kaplan Medical Center, Faculty of Medicine,The Hebrew University of Jerusalem

Journal (Cancer Research)

Surgical Technique for Superior Cervical Ganglionectomy in a Murine Model

Qi Wang¹, Chun-Hao Chen¹, Hongbo Xu², Sylvie Deborde^1,3, Richard J. Wong^1,3

¹Department of Surgery,Memorial Sloan Kettering Cancer Center, ²Department of Otolaryngology-Head and Neck Surgery, Beijing Tongren Hospital,Capital Medical University, ³David M. Rubenstein Center for Pancreatic Cancer Research,Memorial Sloan Kettering Cancer Center

Journal (Cancer Research)

Simple and Fast Rolling Circle Amplification-Based Detection of Topoisomerase 1 Activity in Crude Biological Samples

Josephine Geertsen Keller^1,2, Karol Mizielinski³, Kamilla Vandsø Petersen^1,2, Magnus Stougaard^2,3,4, Birgitta R. Knudsen^1,3, Cinzia Tesauro³

¹Department of Molecular Biology and Genetics,Aarhus University, ²Department of Clinical Medicine,Aarhus University, ³VPCIR Biosciences ApS, ⁴Department of Pathology,Aarhus University Hospital

Journal (Cancer Research)

Biobank for Translational Medicine: Standard Operating Procedures for Optimal Sample Management

Giuseppina Bonizzi*¹, Maria Capra*¹, Cristina Cassi¹, Giulio Taliento¹, Oriana Pala², Elham Sajjadi^2,3, Konstantinos Venetis^2,3, Mariia Ivanova², Massimo Monturano⁴, Giuseppe Renne², Lorenzo Zattoni^1,3, Elena Guerini-Rocco^2,3, Giuseppe Viale^2,3, Roberto Orecchia⁵, Nicola Fusco^1,2,3

¹Biobank for Translational and Digital Medicine Unit,IEO, European Institute of Oncology IRCCS, ²Division of Pathology,IEO, European Institute of Oncology IRCCS, ³Department of Oncology and Hemato-Oncology,University of Milan, ⁴Patient Safety & Risk Management Service,IEO, European Institute of Oncology IRCCS, ⁵Scientific Directorate,IEO, European Institute of Oncology IRCCS

Journal (Cancer Research)

Generating and Imaging Mouse and Human Epithelial Organoids from Normal and Tumor Mammary Tissue Without Passaging

Serena L. Cornelius^1,2, Megan M. Colonnetta^2,3,4,5, Katherine E. Lake^1,2, Clayton A. Smith^1,2, Yu-An Zhang^1,2, Evanthia T. Roussos-Torres⁶, Sangeetha M. Reddy^1,2, Elizabeth H. Chen^2,3,4,5, Isaac S. Chan^1,2,3,4

¹Department of Internal Medicine, Division of Hematology and Oncology,University of Texas Southwestern Medical Center, ²Harold C. Simmons Comprehensive Cancer Center,University of Texas Southwestern Medical Center, ³Department of Molecular Biology,University of Texas Southwestern Medical Center, ⁴Hamon Center for Regenerative Science and Medicine,University of Texas Southwestern Medical Center, ⁵Department of Cell Biology,University of Texas Southwestern Medical Center, ⁶Division of Medical Oncology, Norris Comprehensive Cancer Center, Keck School of Medicine,University of Southern California

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