Advocate Christ Medical Center 1 article published in JoVE Medicine A Novel Approach for the Administration of Medications and Fluids in Emergency Scenarios and Settings Akilesh Honasoge1, Neal Lyons2, Kathleen Hesse3, Braden Parker3, Robert Mokszycki2, Kelly Wesselhoff3, Rolla Sweis2, Erik B. Kulstad3 1College of Medicine, University of Illinois at Chicago, 2Department of Pharmacy, Advocate Christ Medical Center, 3Department of Emergency Medicine, Advocate Christ Medical Center This study presents a novel device that offers an easy route to quickly provide medications and fluids in patients with limited or difficult IV access. This small-diameter device is placed in the distal third of the rectum, allowing for ongoing medication and fluids administration.