Dual-color Correlative Light and Electron Microscopy for the Visualization of Interactions between Mitochondria and Lysosomes

Minkyo Jung; Ji Young Mun

doi:10.3791/67020

Journal

神经科学

Correlative Microscopy Reveals Stress-Induced Mitochondria-Lysosome Interactions

September 27, 2024

Author Spotlight: High-Resolution CLEM Approach for Mapping Mitochondria-Lysosome Interactions

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Minkyo Jung¹, Ji Young Mun¹

¹Neural circuit research group,Korea Brain Research Institute

Summary

This protocol describes a mechanism for using correlative light and electron microscopy to visualize the interaction of mitochondria and lysosomes labeled with mEosEM and APEX2, respectively.

Correlative Microscopy Reveals Stress-Induced Mitochondria-Lysosome Interactions

Author Spotlight: High-Resolution CLEM Approach for Mapping Mitochondria-Lysosome Interactions

Summary

Article