1Neuromuscular and Neurogenetic Disorders of Childhood Section, National Institute of Neurological Disorders and Stroke,National Institutes of Health, 2The Dubowitz Neuromuscular Centre, Molecular Neurosciences Section, Developmental Neurosciences Research and Teaching Department, Great Ormond Street Institute of Child Health,University College London, 3Department of Molecular Microbiology and Immunology,University of Southern California, 4NIHR Great Ormond Street Hospital Biomedical Research Centre, 5Genetics and Genomic Medicine Research and Teaching Department, Great Ormond Street Institute of Child Health,University College London
ここでは、成体マウスにアデノ随伴ウイルス(AAV)を全身投与するためのマウス側尾静脈注射の最適化されたプロトコルについて詳しく説明します。さらに、AAV形質導入を評価するために一般的に使用されるアッセイのプロトコルについても説明します。
