Journal
Immunology and Infection
Immunogenicity Enhancement by Mycobacterium paratuberculosis in Autoimmune Encephalomyelitis

Immunogenicity Enhancement by Mycobacterium paratuberculosis in Autoimmune Encephalomyelitis

May 12, 2023

Author Spotlight: Adjuvant Activity of Mycobacterium paratuberculosis in Enhancing the Immunogenicity of Autoantigens During Experimental Autoimmune Encephalomyelitis

02:51 min
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1,127 Views

Mycobacterial Antigen Preparation

01:38 min
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246 Views

Preparation and Injection of Myelin Oligodendrocyte Glycoprotein (MOG35-55) Emulsion

03:05 min
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328 Views
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1Department of Neurology,Juntendo University, 2Biomedical Research Core Facilities,Juntendo University, 3Neurodegenerative Disorders Collaborative laboratory,RIKEN Center for Brain Science

Summary

English

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Here, we present an alternative protocol to actively induce experimental autoimmune encephalomyelitis in C57BL/6 mice, using the immunogenic epitope myelin oligodendrocyte glycoprotein (MOG)35-55 suspended in incomplete Freund’s adjuvant containing the heat-killed Mycobacterium avium subspecies paratuberculosis.

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