Journal
Immunology and Infection
Establishing a Mouse Model for Candida albicans-Associated Catheter-Related Infection

Establishing a Mouse Model for Candida albicans-Associated Catheter-Related Infection

March 22, 2024

Author Spotlight: Enhancing Candida albicans Detection in Catheter Infections Using Fluorescent Protein Tagging

01:07 min
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Establishment and Evaluation of a Mouse Catheter-Related Infection Model

02:20 min
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1School of Pharmacy, Health Science Center,Xi’an Jiaotong University, 2Key Laboratory of Livestock Infectious Diseases in Northeast China, Ministry of Education, College of Animal Science and Veterinary Medicine,Shenyang Agricultural University

Summary

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We establish a mouse model of C.albicans-associated catheter-related infection (CRI), in which biofilm forms on the catheter, and the interaction between C.albicans and host correlates well with the clinical CRI. This model helps screen therapies for C.albicans biofilm-associated CRI, laying a foundation for clinical transformation.

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