Journal
Neuroscience
Using Chick Embryo Brain as a Model to Study Human Glioblastoma Cell Behavior

Using Chick Embryo Brain as a Model to Study Human Glioblastoma Cell Behavior

May 26, 2023

Author Spotlight: Using the Chick Embryo Brain as a Model for In Vivo and Ex Vivo Analyses of Human Glioblastoma Cell Behavior

02:02 min
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1,792 Views

Injection of Glioblastoma (GBM) Cells into E5 Optic Tectum In Ovo

02:20 min
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345 Views

Live Chick Embryo Brain Dissection and Vibratome Slicing

03:52 min
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473 Views
, , , , , , , ,
1Department of Biological Sciences,University of Delaware, 2Helen F. Graham Cancer Center and Research Institute, Christiana Care, 3Department of Neurosurgery, Winthrop P. Rockefeller Cancer Institute,University of Arkansas for Medical Sciences

Summary

English

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Chick embryos are used for studying human glioblastoma (GBM) brain tumors in ovo and in ex vivo brain slice co-cultures. GBM cell behavior can be recorded by time-lapse microscopy in ex vivo co-cultures, and both preparations can be analyzed at the experimental endpoint by detailed 3D confocal analysis.

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